Berlin: German vaccine maker CureVac on Monday said that interim results from early trials showed that its investigational Covid-19 vaccine candidate, CvnCoV, appeared safe and triggered immune response among volunteers.
The vaccine candidate was generally well tolerated across all tested doses and induced strong binding and neutralising antibody responses in addition to first indication of T cell activation, the company said.
The Phase 1 study has enrolled to date more than 250 healthy individuals aged 18 to 60 years.
Individuals were vaccinated intramuscularly with CVnCoV at escalating dose levels of 2, 4, 6, 8 and 12 microgram on days 1 and 29.
Per dose level, the trial included up to 10 participants who had previously tested positive for a Covid-19 infection (seropositives) to further evaluate the safety and immunogenicity of CVnCoV in this sub-population.
The data support the…