Drug discovery study identifies promising new compound to open constricted airways – health

The experts at the University of South Florida teamed up to advance potential asthma and COPD (chronic obstructive pulmonary disease) treatment that works differently than existing bronchodilators.

Despite the progress made in managing asthma and chronic obstructive pulmonary disease (COPD), poorly controlled symptoms for both respiratory diseases can lead to severe shortness of breath, hospitalizations or even death.

“Only about 50 percent of asthmatics, and an even lower percentage of people with COPD, achieve adequate control of lung inflammation and airway constriction with currently available medications,” said Stephen Liggett, MD, vice dean for research at the University of South Florida Morsani College of Medicine and a USF Health professor of medicine, molecular pharmacology and physiology, and biomedical engineering. “So, we’re clearly missing something from our drug armamentarium to help all these patients.”

Dr. Liggett’s laboratory has discovered…

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