Once Luus was run out by Deepti Sharma (0/31) and Lee was caught and bowled by Radha Yadav (1/25), Laura took the onus on herself to take the team home.
Defending 19 off 12 balls, Harleen dismissed du Preez (10) in the first ball but she conceded two fours, leaving Arundhati Reddy nine to defend in the last over.
Needing six off last two balls, Reddy bowled a no ball which changed the complexion of the game as Laura took the team home in the last ball.
Earlier, opener Shafali set the platform while Ghosh provided the finishing touch as India Women posted a competitive 158 for 4.
Invited to bat, skipper Smriti Mandhana (7) once again fell early as she chased an outside delivery from Ismail only to edge it to the keeper in the second over.
Shafali, who looked watchful initially, smashed three fours in the fourth over to put the bowlers under pressure.
New batter Harleen Doel, who scored a fifty in the first T20I, sent Khaka across the backward point for her first boundary as India scored…